Publications

We kindly request for authors who use STTARR resources to include the following acknowledgement in their publication:
“The authors would like to acknowledge the Spatio-Temporal Targeting and Amplification of Radiation Response (STTARR) program and its affiliated funding agencies.”

Select a year to see a listing of articles published.

  1. Constantine J. Georgiou, Zhongli Cai, Noor Alsaden, Hyungjun Cho, Minou Behboudi, Mitchell A. Winnik, James T. Rutka, and Raymond M. Reilly (2022). Treatment of Orthotopic U251 Human Glioblastoma Multiforme Tumors in NRG Mice by Convection-Enhanced Delivery of Gold Nanoparticles Labeled with the β-Particle-Emitting Radionuclide, 177Lu.
  1. Rezaeeyan, H., Shirzad, R., McKee, T. D., & Saki, N. (2018). Role of chemokines in metastatic niche: new insights along with a diagnostic and prognostic approach. Apmis.
  2. Alhamami, M., Cheng, W., Lyu, Y., Allen, C., Zhang, X.A. and Cheng, H.L.M., 2018. Manganese-porphyrin-enhanced MRI for the detection of cancer cells: A quantitative in vitro investigation with multiple clinical subtypes of breast cancer. PloS one, 13(5), p.e0196998.
  3. Bteich, J., Ernsting, M.J., Mohammed, M.Z., Kiyota, T., McKee, T., Trikha, M., Lowman, H. and Sokoll, K.K., 2018. A Novel Nanoparticle Formulation Derived from Carboxymethyl-Cellulose, Polyethylene Glycol and Cabazitaxel for Chemotherapy Delivery to the Brain. Bioconjugate chemistry.
  4. Dhani, N.C., Lohse, I., Foltz, W.D., Cao, P.J. and Hedley, D.W., 2018. Estimating tumour volume in a primary orthotopic mouse model of human pancreatic cancer using rapid acquisition magnetic resonance imaging. journal of cancer therapeutics and research, 3(1), p.9.
  5. Rezaeeyan, H., Shahrabi, S., McKee, T.D. and Saki, N., 2018. The expression of CD markers in solid tumors: Significance in metastasis and prognostic value. Histology and histopathology, pp.11981-11981.
  6. Li, H., Xie, Y., Liu, Y., Qi, Y., Tang, C., Li, X., Zuo, K., Sun, D., Shen, Y., Pang, D. and Chu, Y., 2018. Alteration in microRNA-25 expression regulate cardiac function via renin secretion. Experimental cell research, 365(1), pp.119-128.
  7. He, C., Li, J., Cai, P., Ahmed, T., Henderson, J.T., Foltz, W.D., Bendayan, R., Rauth, A.M. and Wu, X.Y., 2018. Two‐Step Targeted Hybrid Nanoconstructs Increase Brain Penetration and Efficacy of the Therapeutic Antibody Trastuzumab against Brain Metastasis of HER2‐Positive Breast Cancer. Advanced Functional Materials.
  8. Shahin, S.A., Wang, R., Simargi, S.I., Contreras, A., Echavarria, L.P., Qu, L., Wen, W., Dellinger, T., Unternaehrer, J., Tamanoi, F. and Zink, J.I., 2018. Hyaluronic acid conjugated nanoparticle delivery of siRNA against TWIST reduces tumor burden and enhances sensitivity to cisplatin in ovarian cancer. Nanomedicine: Nanotechnology, Biology and Medicine, 14(4), pp.1381-1394.
  9. Teichman, J., Dodbiba, L., Thai, H., Fleet, A., Morey, T., Liu, L., McGregor, M., Cheng, D., Chen, Z., Darling, G. and Brhane, Y., 2018. Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma. PloS one, 13(5), p.e0194809.
  10. Haynes, J., McKee, T.D., Haller, A., Wang, Y., Leung, C., Gendoo, D.M., Lima-Fernandes, E., Kreso, A., Wolman, R., Szentgyorgyi, E. and Vines, D.C., 2018. Administration of Hypoxia-Activated Prodrug Evofosfamide after Conventional Adjuvant Therapy Enhances Therapeutic Outcome and Targets Cancer-Initiating Cells in Preclinical Models of Colorectal Cancer. Clinical Cancer Research.
  11. Beera, K.G., Li, Y.Q., Dazai, J., Stewart, J., Egan, S., Ahmed, M., Wong, C.S., Jaffray, D.A. and Nieman, B.J., 2018. Altered brain morphology after focal radiation reveals impact of off-target effects: implications for white matter development and neurogenesis. Neuro-oncology, 20(6), pp.788-798.
  12. Zanette, B., Stirrat, E., Jelveh, S., Hope, A. and Santyr, G., 2018. Physiological gas exchange mapping of hyperpolarized 129Xe using spiral‐IDEAL and MOXE in a model of regional radiation‐induced lung injury. Medical physics, 45(2), pp.803-816.
  13. Tang, Q., Lu, J., Zou, C., Shao, Y., Chen, Y., Narala, S., Fang, H., Xu, H., Wang, J., Shen, J. and Khokha, R., 2018. CDH4 is a novel determinant of osteosarcoma tumorigenesis and metastasis. Oncogene, p.1.
  14. Yang, C., Bromma, K., Ciano-Oliveira, C., Zafarana, G., Prooijen, M. and Chithrani, D.B., 2018. Gold nanoparticle mediated combined cancer therapy. Cancer Nanotechnology, 9(1), p.4.
  15. Inoue, M., Enomoto, M., Koike, Y., Di Grappa, M.A., Zhao, X., Yip, K., Huang, S.H., Waldron, J.N., Ikura, M., Liu, F.F. and Bratman, S.V., 2018. Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis. bioRxiv, p.273037.
  16. Xia, D., Casanova, R., Machiraju, D., McKee, T.D., Weder, W., Beck, A.H. and Soltermann, A., 2018. Computationally-Guided Development of a Stromal Inflammation Histologic Biomarker in Lung Squamous Cell Carcinoma. Scientific reports, 8(1), p.3941.
  17. Dunne, Michael, Yannan N. Dou, Danielle M. Drake, Tara Spence, Sávio ML Gontijo, Peter G. Wells, and Christine Allen. “Hyperthermia-mediated drug delivery induces biological effects at the tumor and molecular levels that improve cisplatin efficacy in triple negative breast cancer.” Journal of Controlled Release (2018).
  18. Young, M., Rodenhizer, D., Dean, T., D’Arcangelo, E., Xu, B., Ailles, L. and McGuigan, A.P., 2018. A TRACER 3D Co-Culture tumour model for head and neck cancer. Biomaterials, 164, pp.54-69.
  19. Aghevlian, S., Lu, Y., Winnik, M.A., Hedley, D.W. and Reilly, R.M., 2018. Panitumumab Modified with Metal-Chelating Polymers (MCP) Complexed to 111In and 177Lu–An EGFR-Targeted Theranostic for Pancreatic Cancer. Molecular pharmaceutics.
  20. Yao, W., Xia, K. and Liu, H.W., 2018. Influence of heating on the dynamic tensile strength of two mortars: Experiments and models. International Journal of Impact Engineering, 122, pp.407-418.
  21. Haynes, J., McKee, T.D., Haller, A., Wang, Y., Leung, C., Gendoo, D.M., Lima-Fernandes, E., Kreso, A., Wolman, R., Szentgyorgyi, E. and Vines, D.C., 2018. Administration of Hypoxia-Activated Prodrug Evofosfamide after Conventional Adjuvant Therapy Enhances Therapeutic Outcome and Targets Cancer-Initiating Cells in Preclinical Models of Colorectal Cancer. Clinical Cancer Research.
  22. Stapleton, S., Dunne, M., Milosevic, M., Tran, C.W., Gold, M.J., Vedadi, A., Mckee, T.D., Ohashi, P.S., Allen, C. and Jaffray, D.A., 2018. Radiation and Heat Improve the Delivery and Efficacy of Nanotherapeutics by Modulating Intratumoral Fluid Dynamics. ACS nano, 12(8), pp.7583-7600.
  23. Bernards, N., Ventura, M., Fricke, I.B., Hendriks, B.S., Fitzgerald, J., Lee, H. and Zheng, J., 2018. Liposomal Irinotecan Achieves Significant Survival and Tumor Burden Control in a Triple Negative Breast Cancer Model of Spontaneous Metastasis. Molecular Pharmaceutics, 15(9), pp.4132-4138.
  24. Belliveau, J.G., Jensen, M.D., Stewart, J.M., Solovey, I., Klassen, L.M., Bauman, G.S. and Menon, R.S., 2018. Prediction of radiation necrosis in a rodent model using magnetic resonance imaging apparent transverse relaxation (). Physics in Medicine & Biology, 63(3), p.035010.
  25. Yoshida, M., Oishi, H., Martinu, T., Hwang, D.M., Takizawa, H., Sugihara, J., McKee, T.D., Bai, X., Guana, Z., Lua, C. and Cho, H.R., 2018. Pentraxin 3 deficiency enhances features of chronic rejection in a mouse orthotopic lung transplantation model. Oncotarget, 9(9), p.8489.
  26. Yang, C., Bromma, K., Di Ciano-Oliveira, C., Zafarana, G., van Prooijen, M. and Chithrani, D.B., 2018. Gold nanoparticle mediated combined cancer therapy. Cancer Nanotechnology, 9(1), p.4.
  27. Tang, Q., Lu, J., Zou, C., Shao, Y., Chen, Y., Narala, S., Fang, H., Xu, H., Wang, J., Shen, J. and Khokha, R., 2018. CDH4 is a novel determinant of osteosarcoma tumorigenesis and metastasis. Oncogene, p.1.
  28. Harmatys, K.M., Overchuk, M., Chen, J., Ding, L., Chen, Y., Pomper, M.G. and Zheng, G., 2018. Tuning Pharmacokinetics to Improve Tumor Accumulation of a Prostate-Specific Membrane Antigen-Targeted Phototheranostic Agent. Bioconjugate Chemistry, 29(11), pp.3746-3756.
  29. Keca, J.M., Valic, M.S., Cheng, M.H., Jiang, W., Overchuk, M., Chen, J. and Zheng, G., 2018. Mixed and Matched Metallo‐Nanotexaphyrin for Customizable Biomedical Imaging. Advanced healthcare materials, p.1800857.
  30. Al-saden, N., Cai, Z. and Reilly, R.M., 2018. Tumor uptake and tumor/blood ratios for 89Zr-DFO-trastuzumab-DM1 on microPET/CT images in NOD/SCID mice with human breast cancer xenografts are directly correlated with HER2 expression and response to trastuzumab-DM1. Nuclear medicine and biology, 67, pp.43-51.
  31. Al-Saden, N., Lam, K., Chan, C. and Reilly, R.M., 2018. Positron-Emission Tomography of HER2-Positive Breast Cancer Xenografts in Mice with 89Zr-Labeled Trastuzumab-DM1: A Comparison with 89Zr-Labeled Trastuzumab. Molecular pharmaceutics, 15(8), pp.3383-3393.
  32. Islam, D., Huang, Y., Fanelli, V., Delsedime, L., Wu, S., Khang, J., Han, B., Grassi, A., Li, M., Xu, Y. and Luo, A., 2018. Identification and Modulation of Microenvironment is Crucial for Effective MSC Therapy in Acute Lung Injury. American journal of respiratory and critical care medicine, (ja).
  1. Matsumoto, Y., La Rose, J., Lim, M., Adissu, H.A., Law, N., Mao, X., Cong, F., Mera, P., Karsenty, G., Goltzman, D. and Changoor, A., 2017. Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism. The Journal of clinical investigation, 127(7), pp.2612-2625.
  2. ui, L., Her, S., Borst, G.R., Bristow, R.G., Jaffray, D.A. and Allen, C., 2017. Radiosensitization by gold nanoparticles: Will they ever make it to the clinic?. Radiotherapy and Oncology, 124(3), pp.344-356.
  3. Cui, L., Her, S., Dunne, M., Borst, G.R., De Souza, R., Bristow, R.G., Jaffray, D.A. and Allen, C., 2017. Significant radiation enhancement effects by gold nanoparticles in combination with cisplatin in triple negative breast cancer cells and tumor xenografts. Radiation research, 187(2), pp.147-160.
  4. Allen, C., Her, S. and Jaffray, D.A., 2017. Radiotherapy for Cancer: Present and Future. Advanced drug delivery reviews, 109, p.1.
  5. Zhang, L., Vines, D.C., Scollard, D.A., McKee, T., Komal, T., Ganguly, M., Do, T., Wu, B., Alexander, N., Vali, R. and Shammas, A., 2017. Correlation of Somatostatin Receptor-2 Expression with Gallium-68-DOTA-TATE Uptake in Neuroblastoma Xenograft Models. Contrast media & molecular imaging, 2017.
  6. Cai, Z., Lai, P., Yook, S., Lu, Y., Scollard, D., Winnik, M., Pignol, J.P. and Reilly, R., 2017. Auger-gold-A novel radiation nanomedicine for treatment of small metastases from triple-negative breast cancer. Journal of Nuclear Medicine, 58(supplement 1), pp.677-677.
  7. Wilcox, J.T., Satkunendrarajah, K., Nasirzadeh, Y., Laliberte, A.M., Lip, A., Cadotte, D.W., Foltz, W.D. and Fehlings, M.G., 2017. Corrigendum to” Generating level-dependent models of cervical and thoracic spinal cord injury: Exploring the interplay of neuroanatomy, physiology, and function” Neurobiology of Disease 105 (2017) 194-212. Neurobiology of disease, 108, p.363.
  8. Chaudary, N., Cheung, M., Foltz, W.D., Abdalaty, A.H., Stewart, J.M.P., Lindsay, P.E., Siddiqui, I., Larsen, M., Hill, R.P., Milosevic, M. and Kim, J.H., 2017. Preclinical Development of Targeted Stereotactic Body Radiation Therapy for Pancreatic Cancer. International Journal of Radiation Oncology• Biology• Physics, 99(2), p.S192.
  9. Kalman, N.S., Hugo, G.D., Kahn, J., Zhao, S., Jan, N., Mahon, R.N. and Weiss, E., 2017. Interobserver Reliability in Describing Radiographic Lung Changes After Stereotactic Body Radiation Therapy. International Journal of Radiation Oncology• Biology• Physics, 99(2), p.S196.
  10. Kwon, L.Y., Scollard, D.A. and Reilly, R.M., 2017. 64Cu-Labeled Trastuzumab Fab-PEG24-EGF Radioimmunoconjugates Bispecific for HER2 and EGFR: Pharmacokinetics, Biodistribution, and Tumor Imaging by PET in Comparison to Monospecific Agents. Molecular pharmaceutics, 14(2), pp.492-501.
  11. Lee, S.L., Foltz, W.D., Lee, J., Craig, T., Berlin, A., Chung, P. and Menard, C., 2017. Changes in Apparent Diffusion Coefficient of the Dominant Tumor During Dose-Painted Radiation Therapy and High Dose Rate Brachytherapy for Prostate Cancer. International Journal of Radiation Oncology• Biology• Physics, 99(2), p.E684.
  12. He, C., Li, J., Cai, P., Ahmed, T., Henderson, J.T., Foltz, W.D., Bendayan, R., Rauth, A.M. and Wu, X.Y., 2018. Two‐Step Targeted Hybrid Nanoconstructs Increase Brain Penetration and Efficacy of the Therapeutic Antibody Trastuzumab against Brain Metastasis of HER2‐Positive Breast Cancer. Advanced Functional Materials.
  13. Coolens, C., Driscoll, B., Foltz, W.D., Sinno, N. and Chung, C., 2017. Voxelwise Perfusion and Diffusion Evaluated in Multimodal Imaging Following Radiosurgery for Metastatic Brain Cancer. International Journal of Radiation Oncology• Biology• Physics, 99(2), pp.S195-S196.
  14. Lee, J.K., Zhai, T., Jackson, P., Wen, N. and Siddiqui, S., 2017. Patient Immobilization for Stereotactic Radiosurgery in the Treatment of Malignancies of the Cervical Spine: 9-Point Mask Versus Non-9-Point Mask Immobilization System. International Journal of Radiation Oncology• Biology• Physics, 99(2), pp.E683-E684.
  15. Hysi, E., Wirtzfeld, L. A., May, J. P., Undzys, E., Li, S. D., & Kolios, M. C. (2017). Photoacoustic signal characterization of cancer treatment response: Correlation with changes in tumor oxygenation. Photoacoustics, 5, 25-35.
  16. Beera, K.G., Li, Y.Q., Dazai, J., Stewart, J., Egan, S., Ahmed, M., Wong, C.S., Jaffray, D.A. and Nieman, B.J., 2017. Altered brain morphology after focal radiation reveals impact of off-target effects: implications for white matter development and neurogenesis. Neuro-oncology, p.nox211.
  17. Bullova, P., Cougnoux, A., Marzouca, G., Kopacek, J. and Pacak, K., 2017. Bortezomib alone and in combination with salinosporamid A induces apoptosis and promotes pheochromocytoma cell death in vitro and in female nude mice. Endocrinology, 158(10), pp.3097-3108.
  18. Anderson, J.L., Muraleedharan, R., Oatman, N., Klotter, A., Sengupta, S., Waclaw, R.R., Wu, J., Drissi, R., Miles, L., Raabe, E.H. and Weirauch, M.L., 2017. The transcription factor Olig2 is important for the biology of diffuse intrinsic pontine gliomas. Neuro-oncology, 19(8), pp.1068-1078.
  19. Takayama, K., Inoue, T., Narita, S., Maita, S., Huang, M., Numakura, K., Tsuruta, H., Saito, M., Maeno, A., Satoh, S. and Tsuchiya, N., 2017. Inhibition of the RANK/RANKL signaling with osteoprotegerin prevents castration-induced acceleration of bone metastasis in castration-insensitive prostate cancer. Cancer letters, 397, pp.103-110.
  20. Lin, G.H., Chai, V., Lee, V., Dodge, K., Truong, T., Wong, M., Johnson, L.D., Linderoth, E., Pang, X., Winston, J. and Petrova, P.S., 2017. TTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets. PloS one, 12(10), p.e0187262.
  21. Yao, W., Liu, H.W., Xu, Y., Xia, K. and Zhu, J., 2017. Thermal degradation of dynamic compressive strength for two mortars. Construction and Building Materials, 136, pp.139-152.
  22. Zanette, B., Stirrat, E., Jelveh, S., Hope, A. and Santyr, G., 2017. Physiological gas exchange mapping of hyperpolarized 129Xe using spiral‐IDEAL and MOXE in a model of regional radiation‐induced lung injury. Medical physics.
  23. Yao, W., Xu, Y., Liu, H.W. and Xia, K., 2017. Quantification of thermally induced damage and its effect on dynamic fracture toughness of two mortars. Engineering Fracture Mechanics, 169, pp.74-88.
  24. Woolman, M., Tata, A., Dara, D., Meens, J., D’Arcangelo, E., Perez, C.J., Prova, S.S., Bluemke, E., Ginsberg, H.J., Ifa, D. McGuigan, A., Ailes, L., and Zarrine-Afsar, A. 2017. Rapid determination of the tumour stroma ratio in squamous cell carcinomas with desorption electrospray ionization mass spectrometry (DESI-MS): a proof-of-concept demonstration. Analyst, 142(17), pp.3250-3260.
  25. Zanette, B., Stirrat, E., Jelveh, S., Hope, A. and Santyr, G., 2017. Detection of regional radiation-induced lung injury using hyperpolarized 129Xe chemical shift imaging in a rat model involving partial lung irradiation: Proof-of-concept demonstration. Advances in radiation oncology, 2(3), pp.475-484.
  26. Tabanfar, R., Qiu, J., Chan, H., Aflatouni, N., Weersink, R., Hasan, W. and Irish, J.C., 2017. Real‐time continuous image‐guided surgery: Preclinical investigation in glossectomy. The Laryngoscope, 127(10).
  27. Roberts, C.M., Shahin, S.A., Wen, W., Finlay, J.B., Dong, J., Wang, R., Dellinger, T.H., Zink, J.I., Tamanoi, F. and Glackin, C.A., 2017. Nanoparticle delivery of siRNA against TWIST to reduce drug resistance and tumor growth in ovarian cancer models. Nanomedicine: Nanotechnology, Biology and Medicine, 13(3), pp.965-976.
  28. Belliveau, J.G., Jensen, M.D., Stewart, J.M., Solovey, I., Klassen, M.L., Bauman, G.S. and Menon, R.S., 2017. Prediction of radiation necrosis in a rodent model using magnetic resonance imaging apparent transverse relaxation (R 2*). Physics in medicine and biology.
  29. Maeda, A., Chen, Y., Bu, J., Mujcic, H., Wouters, B.G. and DaCosta, R.S., 2017. In vivo imaging reveals significant tumor vascular dysfunction and increased tumor hypoxia-inducible factor-1α expression induced by high single-dose irradiation in a pancreatic tumor model. International Journal of Radiation Oncology• Biology• Physics, 97(1), pp.184-194.
  30. Vidal, P.M., Karadimas, S.K., Ulndreaj, A., Laliberte, A.M., Tetreault, L., Forner, S., Wang, J., Foltz, W.D. and Fehlings, M.G., 2017. Delayed decompression exacerbates ischemia-reperfusion injury in cervical compressive myelopathy. JCI insight, 2(11).
  31. Fisher, C.J., Niu, C., Foltz, W., Chen, Y., Sidorova-Darmos, E., Eubanks, J.H. and Lilge, L., 2017. ALA-PpIX mediated photodynamic therapy of malignant gliomas augmented by hypothermia. PloS one, 12(7), p.e0181654.
  32. He, C., Cai, P., Li, J., Zhang, T., Lin, L., Abbasi, A.Z., Henderson, J.T., Rauth, A.M. and Wu, X.Y., 2017. Blood-brain barrier-penetrating amphiphilic polymer nanoparticles deliver docetaxel for the treatment of brain metastases of triple negative breast cancer. Journal of Controlled Release, 246, pp.98-109.
  33. Zeng, K., Tian, L., Sirek, A., Shao, W., Liu, L., Chiang, Y.T., Chernoff, J., Ng, D.S., Weng, J. and Jin, T., 2017. Pak1 mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression. Journal of molecular cell biology, 9(5), pp.384-394.
  34. Woolman, M., Ferry, I., Kuzan-Fischer, C.M., Wu, M., Zou, J., Kiyota, T., Isik, S., Dara, D., Aman, A., Das, S., Taylor, M.D., Rutka, J.T., Ginsberg H.J., and Zarrine-Afsar, A. 2017. Rapid determination of medulloblastoma subgroup affiliation with mass spectrometry using a handheld picosecond infrared laser desorption probe. Chemical science, 8(9), pp.6508-6519.
  35. Lu, Y., Boyle, A.J., Cao, P.J., Hedley, D., Reilly, R.M. and Winnik, M.A., 2017. EGFR-targeted metal chelating polymers (MCPs) harboring multiple pendant PEG2K chains for microPET/CT imaging of patient-derived pancreatic cancer xenografts. ACS Biomaterials Science & Engineering, 3(3), pp.279-290.
  36. Lai, P., Cai, Z., Pignol, J.P., Lechtman, E., Mashouf, S., Lu, Y., Winnik, M.A., Jaffray, D.A. and Reilly, R.M., 2017. Monte Carlo simulation of radiation transport and dose deposition from locally released gold nanoparticles labeled with 111In, 177Lu or 90Y incorporated into tissue implantable depots. Physics in Medicine & Biology, 62(22), p.8581.
  37. Aghevlian, S., Lu, Y., Winnik, M.A., Hedley, D.W. and Reilly, R.M., 2018. Panitumumab Modified with Metal-Chelating Polymers (MCP) Complexed to 111In and 177Lu–An EGFR-Targeted Theranostic for Pancreatic Cancer. Molecular pharmaceutics.
  38. Chang, Y.C.C., Ackerstaff, E., Tschudi, Y., Jimenez, B., Foltz, W., Fisher, C., Lilge, L., Cho, H., Carlin, S., Gillies, R.J. and Balagurunathan, Y., 2017. Delineation of tumor habitats based on dynamic contrast enhanced MRI. Scientific reports, 7(1), p.9746.
  39. Lam, K., Chan, C. and Reilly, R.M., 2017, January. Development and preclinical studies of 64Cu-NOTA-pertuzumab F (ab′) 2 for imaging changes in tumor HER2 expression associated with response to trastuzumab by PET/CT. In MAbs (Vol. 9, No. 1, pp. 154-164). Taylor & Francis.
  1. Wang, C. R., Mahmood, J., Zhang, Q. R., Vedadi, A., Warrington, J., Ou, N., … & Lu, Q. B. (2016). In Vitro and In Vivo Studies of a New Class of Anticancer Molecules for Targeted Radiotherapy of Cancer. Molecular Cancer Therapeutics, molcanther-0862.
  2. Au, B. C., Lee, C. J., Lopez-Perez, O., Foltz, W., Felizardo, T. C., Wang, J., … & Jaffray, D. A. (2016). Direct Lymph Node Vaccination of Lentivector/Prostate-Specific Antigen is Safe and Generates Tissue-Specific Responses in Rhesus Macaques. Biomedicines, 4(1), 6.
  3. Tata, A., Gribble, A., Ventura, M., Ganguly, M., Bluemke, E., Ginsberg, H. J., … & Zarrine-Afsar, A. (2016). Wide-field tissue polarimetry allows efficient localized mass spectrometry imaging of biological tissues. Chemical Science.
  4. Juneja, S. C., Viswanathan, S., Ganguly, M., & Veillette, C. (2016). A Simplified Method for the Aspiration of Bone Marrow from Patients Undergoing Hip and Knee Joint Replacement for Isolating Mesenchymal Stem Cells and In Vitro Chondrogenesis. Bone Marrow Research, 2016.
  5. Kim, S. M., Haider, M. A., Jaffray, D. A., & Yeung, I. W. (2016). Improved accuracy of quantitative parameter estimates in dynamic contrast-enhanced CT study with low temporal resolution. Medical physics, 43(1), 388-400.
  6. Dal Pra, A., Locke, J. A., Borst, G., Supiot, S., & Bristow, R. G. (2016). Mechanistic Insights into Molecular Targeting and Combined Modality Therapy for Aggressive, Localized Prostate Cancer. Frontiers in oncology, 6.
  7. Rodenhizer, Darren, et al. “A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients.”Nature materials 15.2 (2016): 227-234.
  8. Morrissy, A. Sorana, et al. “Divergent clonal selection dominates medulloblastoma at recurrence.” Nature 529.7586 (2016): 351-357.
  9. Edgar, L. J., Vellanki, R. N., McKee, T. D., Hedley, D., Wouters, B. G., & Nitz, M. (2016). Isotopologous Organotellurium Probes Reveal Dynamic Hypoxia In Vivo with Cellular Resolution. Angewandte Chemie, 128(42), 13353-13357.
  10. Bilkey, J., Tata, A., McKee, T. D., Porcari, A. M., Bluemke, E., Woolman, M., … & Zarrine-Afsar, A. (2016). Variations in the Abundance of Lipid Biomarker Ions in Mass Spectrometry Images Correlate to Tissue Density. Analytical Chemistry, 88(24), 12099-12107.
  11. Moonen, G., Satkunendrarajah, K., Wilcox, J. T., Badner, A., Mothe, A., Foltz, W., … & Tator, C. H. (2016). A New Acute Impact-Compression Lumbar Spinal Cord Injury Model in the Rodent. Journal of neurotrauma, 33(3), 278-289.
  12. Stapleton, S., Mirmilshteyn, D., Zheng, J., Allen, C., & Jaffray, D. A. (2016). Spatial Measurements of Perfusion, Interstitial Fluid Pressure and Liposomes Accumulation in Solid Tumors. JoVE (Journal of Visualized Experiments), (114), e54226-e54226.
  13. Hammoud, L., Adams, J. R., Loch, A. J., Marcellus, R. C., Uehling, D. E., Aman, A., … & Egan, S. E. (2016). Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay. Stem cell reports, 7(4), 787-801.
  14. Her, S., Cui, L., Bristow, R. G., & Allen, C. (2016). Dual Action Enhancement of Gold Nanoparticle Radiosensitization by Pentamidine in Triple Negative Breast Cancer. Radiation research, 185(5), 549-562.
  15. Kostron, H., & Hasan, T. (Eds.). (2016). Photodynamic Medicine: From Bench to Clinic (Vol. 15). Royal Society of Chemistry.
  16. Sauvé, M., Hui, S. K., Dinh, D. D., Foltz, W. D., Momen, A., Nedospasov, S. A., … & Bolz, S. S. (2016). Tumor necrosis factor/sphingosine-1-phosphate signaling augments resistance artery myogenic tone in diabetes. Diabetes, db151450.
  17. Roberts, C. M., Shahin, S. A., Wen, W., Finlay, J. B., Dong, J., Wang, R., … & Glackin, C. A. (2016). Nanoparticle delivery of siRNA against TWIST to reduce drug resistance and tumor growth in ovarian cancer models. Nanomedicine: Nanotechnology, Biology and Medicine.
  18. Sun, Y., & Chakrabartty, A. (2016). Cost-effective elimination of lipofuscin fluorescence from formalin-fixed brain tissue by white phosphor light emitting diode array. Biochemistry and Cell Biology, 94(6), 545-550.
  19. May, J. P., Hysi, E., Wirtzfeld, L. A., Undzys, E., Li, S. D., & Kolios, M. C. (2016). Photoacoustic Imaging of Cancer Treatment Response: Early Detection of Therapeutic Effect from Thermosensitive Liposomes. PLoS One, 11(10), e0165345.
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  1. Finlay, J., Roberts, C. M., Dong, J., Zink, J. I., Tamanoi, F., & Glackin, C. A. (2015). Mesoporous silica nanoparticle delivery of chemically modified siRNA against TWIST1 leads to reduced tumor burden. Nanomedicine: Nanotechnology, Biology and Medicine, 11(7), 1657-1666.
  2. Her, S., Jaffray, D. A., & Allen, C. (2015). Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements. Advanced drug delivery reviews.
  3. Chen, Y., Di Grappa, M. A., Molyneux, S. D., McKee, T. D., Waterhouse, P., Penninger, J. M., & Khokha, R. (2015). RANKL blockade prevents and treats aggressive osteosarcomas. Science translational medicine, 7(317), 317ra197-317ra197.
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  5. Abbasi, A. Z., Prasad, P., Cai, P., He, C., Foltz, W. D., Amini, M. A., … & Wu, X. Y. (2015). Manganese oxide and docetaxel co-loaded fluorescent polymer nanoparticles for dual modal imaging and chemotherapy of breast cancer. Journal of Controlled Release, 209, 186-196.
  6. Ernsting, M. J., Hoang, B., Lohse, I., Undzys, E., Cao, P., Do, T., … & Li, S. D. (2015). Targeting of metastasis-promoting tumor-associated fibroblasts and modulation of pancreatic tumor-associated stroma with a carboxymethylcellulose-docetaxel nanoparticle. Journal of Controlled Release, 206, 122-130.
  7. Lee, H., Zheng, J., Gaddy, D., Orcutt, K. D., Leonard, S., Geretti, E., … & Wickham, T. (2015). A gradient-loadable 64 Cu-chelator for quantifying tumor deposition kinetics of nanoliposomal therapeutics by positron emission tomography. Nanomedicine: Nanotechnology, Biology and Medicine, 11(1), 155-165.
  8. Yagi, K., Lidington, D., Wan, H., Fares, J. C., Meissner, A., Sumiyoshi, M., … & Nagahiro, S. (2015). Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage. Stroke, 46(8), 2260-2270.
  9. Geretti, E., Leonard, S. C., Dumont, N., Lee, H., Zheng, J., De Souza, R., … & Nielsen, U. B. (2015). Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302). Molecular cancer therapeutics, 14(9), 2060-2071.
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  11. Karadimas, S., Laliberte, A., Tetreault, L., Chung, Y. S., Foltz, W. D., Arnold, P. M., & Fehlings, M. G. (2015). Riluzole Attenuates the Decompression-Induced Ischemia Reperfusion Injury and Enhances the Beneficial Impact of Decompression in Cervical Spondylotic Myelopathy. The Spine Journal, 15(10), S158-S159.
  12. Shiah, Y. J., Tharmapalan, P., Casey, A. E., Joshi, P. A., McKee, T. D., Jackson, H. W., … & Waterhouse, P. D. (2015). A progesterone-CXCR4 axis controls mammary progenitor cell fate in the adult gland. Stem cell reports,4(3), 313-322.
  13. Stares, E. (2015). Novel Magnetic Materials Based on Macrocyclic Ligands: Towards High Relaxivity Contrast Agents and Mononuclear Single-Molecule Magnets.
  14. Martinez, L., Ermolova, N. V., Ishikawa, T. O., Stout, D. B., Herschman, H. R., & Spencer, M. J. (2015). A reporter mouse for optical imaging of inflammation in mdx muscles. Skeletal muscle, 5(1), 1.
  15. Kubant, R., Poon, A. N., Sánchez-Hernández, D., Domenichiello, A. F., Huot, P. S. P., Pannia, E., … & Anderson, G. H. (2015). A comparison of effects of lard and hydrogenated vegetable shortening on the development of high-fat diet-induced obesity in rats. Nutrition & Diabetes, 5(12), e188.
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  17. Finlay, J., Roberts, C. M., Lowe, G., Loeza, J., Rossi, J. J., & Glackin, C. A. (2015). RNA-based TWIST1 inhibition via dendrimer complex to reduce breast cancer cell metastasis. BioMed research international, 2015.
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  22. Muhanna, N., MacDonald, T. D., Chan, H., Jin, C. S., Burgess, L., Cui, L., … & Zheng, G. (2015). Multimodal Nanoparticle for Primary Tumor Delineation and Lymphatic Metastasis Mapping in a Head‐and‐Neck Cancer Rabbit Model. Advanced healthcare materials, 4(14), 2164-2169.
  23. Gladwish, A. P., Han, K., & Foltz, W. D. (2015). Variation in apparent diffusion coefficient measurements among women with locally advanced cervical cancer. Radiotherapy and Oncology, 117(3), 532-535.
  24. Velauthapillai, N. (2015). Oral Antioxidants for Radioprotection during Medical Imaging Examinations (Doctoral dissertation).
  25. Foltz, W. D., Porter, D. A., Simeonov, A., Aleong, A., Jaffray, D., Chung, P., … & Ménard, C. (2015). Readout-segmented echo-planar diffusion-weighted imaging improves geometric performance for image-guided radiation therapy of pelvic tumors. Radiotherapy and Oncology, 117(3), 525-531.
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  2. Mikhail, A. S., Eetezadi, S., Ekdawi, S. N., Stewart, J., & Allen, C. (2014). Image-based analysis of the size-and time-dependent penetration of polymeric micelles in multicellular tumor spheroids and tumor xenografts. International journal of pharmaceutics, 464(1), 168-177.
  3. Han, S. M., Wan, H., Kudo, G., Foltz, W. D., Vines, D. C., Green, D. E., … & Ai, J. (2014). Molecular alterations in the hippocampus after experimental subarachnoid hemorrhage. Journal of Cerebral Blood Flow & Metabolism,34(1), 108-117.
  4. Montanari, S., Wang, X. H., Yannarelli, G., Dayan, V., Berger, T., Zocche, L., … & Keating, A. (2014). Development and characterization of a new inbred transgenic rat strain expressing DsRed monomeric fluorescent protein. Transgenic research, 23(5), 779-793.
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  6. Mahmood, J., Jelveh, S., Zaidi, A., Doctrow, S. R., Medhora, M., & Hill, R. P. (2014). Targeting the Renin–Angiotensin System Combined With an Antioxidant Is Highly Effective in Mitigating Radiation-Induced Lung Damage. International Journal of Radiation Oncology* Biology* Physics, 89(4), 722-728.
  7. Berlin, A., Lalonde, E., Zafarana, G., Sykes, J., Ramnarine, V. R., Lam, W., … & Bristow, R. G. (2014, February). Using NBN to predict biochemical relapse following image-guided radiotherapy (IGRT) for intermediate-risk prostate cancer (IR-PCa). In ASCO Annual Meeting Proceedings (Vol. 32, No. 4_suppl, p. 26).
  8. Zheng, J., De Souza, R., Jaffray, D., & Allen, C. (2014). Nanotechnology for Multimodality Imaging: Applications in Disease Detection and Treatment Guidance. In HANDBOOK OF NANOBIOMEDICAL RESEARCH: Fundamentals, Applications and Recent Developments: Volume 3. Applications in Diagnostics (pp. 145-193).
  9. Dhani, N. C., Lohse, I., Foltz, W. D., Cao, P. J., & Hedley, D. W. (2014). Estimating tumour volume in a primary orthotopic mouse model of human pancreatic cancer using rapid acquisition magnetic resonance imaging.
  10. Bartzsch, S. (2014). Microbeam Radiation Therapy–physical and biological aspects of a new cancer therapy and development of a treatment planning system.
  11. Moon, E. S., Karadimas, S. K., Yu, W. R., Austin, J. W., & Fehlings, M. G. (2014). Riluzole attenuates neuropathic pain and enhances functional recovery in a rodent model of cervical spondylotic myelopathy. Neurobiology of disease, 62, 394-406.
  12. Dou, Y. N., Zheng, J., Foltz, W. D., Weersink, R., Chaudary, N., Jaffray, D. A., & Allen, C. (2014). Heat-activated thermosensitive liposomal cisplatin (HTLC) results in effective growth delay of cervical carcinoma in mice. Journal of Controlled Release, 178, 69-78.
  13. Forgione, N., Karadimas, S. K., Foltz, W. D., Satkunendrarajah, K., Lip, A., & Fehlings, M. G. (2014). Bilateral contusion-compression model of incomplete traumatic cervical spinal cord injury. Journal of neurotrauma,31(21), 1776-1788.
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  26. Moonen, G. (2014). Development and Characterization of an Acute Impact-Compression Lumbar Spinal Cord Injury Model in the Rat (Doctoral dissertation).
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  1. Stapleton, S., Milosevic, M., Allen, C., Zheng, J., Dunne, M., Yeung, I., & Jaffray, D. A. (2013). A mathematical model of the enhanced permeability and retention effect for liposome transport in solid tumors. PloS one, 8(12), e81157.
  2. Bae, Y. H., Mrsny, R. J., & Park, K. (2013). Cancer Targeted Drug Delivery. Springer New York.
  3. Ekdawi, S. N., Mikhail, A. S., Stapleton, S., Zheng, J., Eetezadi, S., Jaffray, D. A., & Allen, C. (2013). Long circulation and tumor accumulation. InCancer Targeted Drug Delivery (pp. 543-571). Springer New York.
  4. Mikhail, A. S., Eetezadi, S., & Allen, C. (2013). Multicellular tumor spheroids for evaluation of cytotoxicity and tumor growth inhibitory effects of nanomedicines in vitro: a comparison of docetaxel-loaded block copolymer micelles and Taxotere®. PloS one, 8(4), e62630.
  5. Chang, Q., Foltz, W. D., Chaudary, N., Hill, R. P., & Hedley, D. W. (2013). Tumor–stroma interaction in orthotopic primary pancreatic cancer xenografts during hedgehog pathway inhibition. International Journal of Cancer, 133(1), 225-234.
  6. Shalviri, A., Foltz, W. D., Cai, P., Rauth, A. M., & Wu, X. Y. (2013). Multifunctional terpolymeric MRI contrast agent with superior signal enhancement in blood and tumor. Journal of Controlled Release, 167(1), 11-20.
  7. Cui, L., Zahedi, P., Saraceno, J., Bristow, R., Jaffray, D., & Allen, C. (2013). Neoplastic cell response to tiopronin-coated gold nanoparticles.Nanomedicine: Nanotechnology, Biology and Medicine, 9(2), 264-273.
  8. Klinz, S. G., Zheng, J., De Souza, R., Dunne, M., Cain, J., Kim, J., … & Fitzgerald, J. (2013). Abstract C293: Irinotecan sucrosofate liposome injection, MM-398, demonstrates superior activity and control of hypoxia as measured through longitudinal imaging using [18F] FAZA PET compared to free irinotecan in a colon adenocarcinoma xenograft model. Molecular Cancer Therapeutics, 12(11 Supplement), C293-C293.
  9. Chattopadhyay, N., Cai, Z., Kwon, Y. L., Lechtman, E., Pignol, J. P., & Reilly, R. M. (2013). Molecularly targeted gold nanoparticles enhance the radiation response of breast cancer cells and tumor xenografts to X-radiation. Breast cancer research and treatment, 137(1), 81-91.
  10. Lohse, I., Cao, P., Do, T., Ibrahimov, E., Tsao, M. S., & Hedley, D. W. (2013). Abstract B282: The PLK-4 inhibitor CFI-400945 reduces tumor growth in patient-derived pancreatic xenografts. Molecular Cancer Therapeutics,12(11 Supplement), B282-B282.
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  13. Zannella, V. E., Dal Pra, A., Muaddi, H., McKee, T. D., Stapleton, S., Sykes, J., … & Wouters, B. G. (2013). Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response. Clinical Cancer Research, 19(24), 6741-6750.
  14. Murakami, M., Ernsting, M. J., Undzys, E., Holwell, N., Foltz, W. D., & Li, S. D. (2013). Docetaxel Conjugate Nanoparticles That Target α-Smooth Muscle Actin–Expressing Stromal Cells Suppress Breast Cancer Metastasis. Cancer research, 73(15), 4862-4871.
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  16. Foomany, F. H., Beheshti, M., Magtibay, K., Masse, S., Foltz, W., Sevaptsidis, E., … & Umapathy, K. (2013, July). Analysis of reliability metrics and quality enhancement measures in current density imaging. In Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE (pp. 4394-4397). IEEE.
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  18. Ding, H., Helguera, G., Rodríguez, J. A., Markman, J., Luria-Pérez, R., Gangalum, P., … & Holler, E. (2013). Polymalic acid nanobioconjugate for simultaneous immunostimulation and inhibition of tumor growth in HER2/neu-positive breast cancer. Journal of Controlled Release, 171(3), 322-329.
  19. Hoang, B., Ekdawi, S. N., Reilly, R. M., & Allen, C. (2013). Active targeting of block copolymer micelles with trastuzumab fab fragments and nuclear localization signal leads to increased tumor uptake and nuclear localization in HER2-overexpressing xenografts. Molecular pharmaceutics, 10(11), 4229-4241.
  20. MacDonald, T. (2013). Metalloporphysomes: Engineering New Metalloporphyrin Nanoparticles (Doctoral dissertation).
  21. Holler, E., Penichet, M. L., & Ljubimova, J. Y. (2013). Polymalic acid nanobioconjugate for simultaneous immunostimulation and inhibition of tumor growth in HER2/neu-positive breast cancer.
  22. Chung, C., Jalali, S., Foltz, W., Burrell, K., Wildgoose, P., Lindsay, P., … & Zadeh, G. (2013). Imaging biomarker dynamics in an intracranial murine glioma study of radiation and antiangiogenic therapy. International Journal of Radiation Oncology* Biology* Physics, 85(3), 805-812.
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  1. Jelveh S, Chithrani DB. Gold nanostructures as a platform for combinational therapy in future cancer therapeutics. Cancers 3(1):1081-1110. 2011
  2. Mahmood J, Jelveh S, Calveley V, Zaidi A, Doctrow SR, Hill RP. Mitigation of lung injury after accidental exposure to radiation. Radiat Res 176(6):770-80. Dec 2011.
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  6. Fraser M, Zhao H, Luoto KR, Lundin C, Coackley CL, Chan N, Joshua AM, Bismar TA, Evans A, Helleday T, Bristow RG. PTEN Deletion in Prostate Cancer Cells Does Not Associate With Loss of RAD51 Function: Implications for Radiotherapy and Chemotherapy. Clin Cancer Res. Nov 2011.
  7. McLarty K, Moran MD, Scollard DA, Chan C, Sabha N, Mukherjee J, Guha A, McLaurin J, Nitz M, Houle S, Wilson AA, Reilly RM, Vasdev N. Comparisons of [18F]-1-deoxy-1-fluoro-scyllo-inositol with [18F]-FDG for PET imaging of inflammation, breast and brain cancer xenografts in athymic mice. Nucl Med Biol 38(7):953-9. Oct 2011.
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  9. Zhao H, Luoto KR, Meng AX, Bristow RG. The receptor tyrosine kinase inhibitor amuvatinib (MP470) sensitizes tumor cells to radio- and chemo-therapies in part by inhibiting homologous recombination. Radiother Oncol 101(1):59-65. Oct 2011.
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  16. Yu Z, Shao W, Chiang Y, Foltz W, Zhang Z, Ling W, Fantus IG, Jin T. Oltipraz upregulates the nuclear respiratory factor 2 alpha subunit (NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice. Diabetologia 54(4):922-34. Apr 2011.
  17. Shuhendler AJ, Prasad P, Chan HK, Gordijo CR, Soroushian B, Kolios M, Yu K, O’Brien PJ, Rauth AM, Wu XY. Hybrid Quantum Dot−Fatty Ester Stealth Nanoparticles: Toward Clinically Relevant in Vivo Optical Imaging of Deep Tissue. ACS Nano 5 (3), 1958-1966. Mar 2011.
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  1. McLarty K, Fasih A, Scollard DA, Done SJ, Vines DC, Green DE, Costantini DL, Reilly RM. 18F-FDG small-animal PET/CT differentiates trastuzumab- responsive from unresponsive human breast cancer xenografts in athymic mice. J Nucl Med 50(11):1848-56. Nov 2009.
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  1. Lunt SJ, Fyles A, Hill RP, Milosevic M. Interstitial fluid pressure in tumors: therapeutic barrier and biomarker of angiogenesis. Future Oncol 4(6):793-802. Dec 2008.
  2. Kim SM, Cho YB, Haider MA, Milosevic M, Yeung IW. Multiphasic contrast injection for improved precision of parameter estimates in functional CT. Med Phys 35(12):5921-33. Dec 2008.
  3. Liu SK, Coackley C, Krause M, Jalali F, Chan N, Bristow RG. A novel poly(ADP-ribose) polymerase inhibitor, ABT-888, radiosensitizes malignant human cell lines under hypoxia, Radiother Oncol 88(2):258-68. Aug 2008.
  4. Lunt SJ, Kalliomaki TM, Brown A, Yang VX, Milosevic M, Hill RP. Interstitial fluid pressure, vascularity and metastasis in ectopic, orthotopic and spontaneous tumours. BMC Cancer 8:2. Jan 2008.
  5. Zheng J, Jaffray DA, Allen C. Nanosystems for Multimodality in vivo Imaging. Book Title: Multifunctional Pharmaceutical Nanocarriers. Editor: Vladimir Torchilin. Publisher: Springer New York, 2008.
  6. Hoisak, J. D., Zheng, J., Allen, C., & Jaffray, D. A. (2008, March). Improved CT and MR image registration with the introduction of a dual-modality contrast agent: performance assessment using quantitative and information theoretic methods. In Medical Imaging (pp. 69140Z-69140Z). International Society for Optics and Photonics.
  1. Zheng J, Liu J, Dunne M, Jaffray DA, Allen C. In Vivo Performance of a Liposomal Vascular Contrast Agent for CT and MR-Based Image Guidance Applications. Pharm Res 24(6):1193-201. Jun 2007.
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